Doctor Doom Synergy Guide

Adding Doctor Doom with Annihilus activates the 'Fantastic Rage' synergy bonus where Heavy Attacks for Doctor Doom are guaranteed critical hits while the Opponent is suffering from a Stagger effect. Please note this is a solo synergy which does not stack.

Adding Doctor Doom with Diablo activates the 'Fantastic Rage' synergy bonus where Heavy Attacks for Doctor Doom are guaranteed critical hits while the Opponent is suffering from a Stagger effect. Please note this is a solo synergy which does not stack.

A solo synergy for Doctor Doom, no partner required, 'I Answer to No One' increases the Attack Rating of Doctor Doom by 10% for each knocked out team member! Please note this does not stack.

Adding Doctor Doom with Doctor Octopus activates the 'Genius Ingenuity' synergy bonus where Shock and Incinerate Debuffs for Doctor Doom have a +20% increased Potency. Please note this is a solo synergy which does not stack.

Adding Doctor Doom with Doctor Strange activates the 'Sorcery Reversal' synergy bonus so when Doctor Doom activates the Aura of Haazareth it has a 50% chance to Purify all Degeneration, Poison, Incinerate, Bleed and Cold Snap Debuffs. Please note this is a solo synergy which does not stack.

Adding Doctor Doom with Human Torch activates the 'Nemesis' synergy bonus, increasing 'Attack' for the whole team.

Adding Doctor Doom with Invisible Woman activates the 'Nemesis' synergy bonus, increasing 'Attack' for the whole team.

Adding Doctor Doom with M.O.D.O.K. activates the 'Enhanced Forcefield' synergy bonus where Doctor Doom gains +15% Perfect Block chance. Please note this is a solo synergy which does not stack.

Add Mole Man to a team with Doctor Doom to activate the 'Fantastic Fiends' synergy bonus so that while Mole Man is Frenzied his attacks lower Defensive Ability Accuracy by 50% when fighting against the #Fantastic Four and Doctor Doom gets a 20% chance to Purify a Debuff. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Add Platinumpool to a team with Doctor Doom to activate the 'Deathwish' synergy bonus which increases the chance for Platinumpool to draw the Sumopool Card. This is a Solo synergy which does not stack.

Adding Doctor Doom with Red Skull activates the 'Enhanced Forcefield' synergy bonus where Doctor Doom gains +15% Perfect Block chance. Please note this is a solo synergy which does not stack.

Add Silver Surfer to a team with Doctor Doom to activate the 'Enemies' synergy bonus, increasing 'Critical Rating' for the whole team.

Add Squirrel Girl to a team with Doctor Doom to activate the 'Beat Up the Universe' synergy bonus so that once per fight when Tippy Toe would Purify all non-damaging Debuffs on Squirrel Girl it will also Purify 1 damaging Debuff and Aura of Haazareth for Doctor Doom lasts an additional 2 seconds. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Adding Doctor Doom with Symbiote Supreme activates the 'Sorcery Reversal' synergy bonus so when Doctor Doom activates the Aura of Haazareth it has a 50% chance to Purify all Degeneration, Poison, Incinerate, Bleed and Cold Snap Debuffs. Please note this is a solo synergy which does not stack.

Adding Doctor Doom with Thing activates the 'Nemesis' synergy bonus, increasing 'Attack' for the whole team.