
Doctor Doom Synergy Guide
Doctor Doom is a Mystic class champion in the Contest of Champions who forms a synergy with 16 other characters, available as a 3-Star, 4-Star and 5-Star champion.
Leaving his tribe in Latveria, Victor Von Doom moved to the United States to study at the Empire State University where he combined sorcery and technology to create fantastic inventions. Disregarding the warnings of fellow classmate Reed Richards, one of his inventions malfunctioned resulting in an explosion that severely damaged his face. Expelled after the incident, Victor began travelling the world eventually collapsing exhausted, on a Tibetan mountainside where he was rescued by a clan of monks. Mastering their discipline and forging himself a suit of armor, Victor took on the mantle Doctor Doom, his mission to serve revenge on those he holds responsible for his accident.
Synergy Bonuses
- 'I Answer to No One' with Doctor Doom
- 'Nemesis' with Thing, Human Torch, Invisible Woman or Mister Fantastic
- 'Fantastic Rage' with Diablo or Annihilus
- 'Enhanced Forcefield' with M.O.D.O.K. or Red Skull
- 'Genius Ingenuity' with Mister Fantastic or Doctor Octopus
- 'Sorcery Reversal' with Doctor Strange or Symbiote Supreme

Annihilus
Adding Doctor Doom with Annihilus activates the 'Fantastic Rage' synergy bonus where Heavy Attacks for Doctor Doom are guaranteed critical hits while the Opponent is suffering from a Stagger effect. Please note this is a solo synergy which does not stack.

Doctor Doom Synergy with Annihilus
Star | Synergy | Bonus |
---|---|---|
Doctor Doom 4 Star | Fantastic Rage | See Notes |
Doctor Doom 5 Star | Fantastic Rage | See Notes |
Diablo
Adding Doctor Doom with Diablo activates the 'Fantastic Rage' synergy bonus where Heavy Attacks for Doctor Doom are guaranteed critical hits while the Opponent is suffering from a Stagger effect. Please note this is a solo synergy which does not stack.

Doctor Doom Synergy with Diablo
Star | Synergy | Bonus |
---|---|---|
Doctor Doom 4 Star | Fantastic Rage | See Notes |
Doctor Doom 5 Star | Fantastic Rage | See Notes |
Doctor Doom
A solo synergy for Doctor Doom, no partner required, 'I Answer to No One' increases the Attack Rating of Doctor Doom by 10% for each knocked out team member! Please note this does not stack.

Doctor Doom Synergy with Doctor Doom
Star | Synergy | Bonus |
---|---|---|
Doctor Doom 3 Star | I Answer to No One | See Notes |
Doctor Doom 4 Star | I Answer to No One | See Notes |
Doctor Doom 5 Star | I Answer to No One | See Notes |
Doctor Octopus
Adding Doctor Doom with Doctor Octopus activates the 'Genius Ingenuity' synergy bonus where Shock and Incinerate Debuffs for Doctor Doom have a +20% increased Potency. Please note this is a solo synergy which does not stack.

Doctor Doom Synergy with Doctor Octopus
Star | Synergy | Bonus |
---|---|---|
Doctor Doom 4 Star | Genius Ingenuity | See Notes |
Doctor Doom 5 Star | Genius Ingenuity | See Notes |
Doctor Strange
Adding Doctor Doom with Doctor Strange activates the 'Sorcery Reversal' synergy bonus so when Doctor Doom activates the Aura of Haazareth it has a 50% chance to Purify all Degeneration, Poison, Incinerate, Bleed and Cold Snap Debuffs. Please note this is a solo synergy which does not stack.

Doctor Doom Synergy with Doctor Strange
Star | Synergy | Bonus |
---|---|---|
Doctor Doom 4 Star | Sorcery Reversal | See Notes |
Doctor Doom 5 Star | Sorcery Reversal | See Notes |
Human Torch
Adding Doctor Doom with Human Torch activates the 'Nemesis' synergy bonus, increasing 'Attack' for the whole team.

Doctor Doom Synergy with Human Torch
Star | Synergy | Bonus |
---|---|---|
Doctor Doom 3 Star | Nemesis Level 2 | +5% Attack |
Doctor Doom 4 Star | Nemesis Level 3 | +6% Attack |
Doctor Doom 5 Star | Nemesis Level 3 | +6% Attack |
Invisible Woman
Adding Doctor Doom with Invisible Woman activates the 'Nemesis' synergy bonus, increasing 'Attack' for the whole team.

Doctor Doom Synergy with Invisible Woman
Star | Synergy | Bonus |
---|---|---|
Doctor Doom 3 Star | Nemesis Level 2 | +5% Attack |
Doctor Doom 4 Star | Nemesis Level 3 | +6% Attack |
Doctor Doom 5 Star | Nemesis Level 3 | +6% Attack |
M.O.D.O.K.
Adding Doctor Doom with M.O.D.O.K. activates the 'Enhanced Forcefield' synergy bonus where Doctor Doom gains +15% Perfect Block chance. Please note this is a solo synergy which does not stack.

Doctor Doom Synergy with M.O.D.O.K.
Star | Synergy | Bonus |
---|---|---|
Doctor Doom 4 Star | Enhanced Forcefield | See Notes |
Doctor Doom 5 Star | Enhanced Forcefield | See Notes |
Mister Fantastic
Team up the Doctor Doom with Mister Fantastic to activate multiple synergies. Doctor Doom activates the 'Genius Ingenuity' solo synergy (does not stack) where his Shock and Incinerate Debuffs have a +20% increased Potency and in addition he also activates the 'Nemesis' synergy which increases 'Attack' for the whole team. Mister Fantatic activates the unique synergy 'College Rivals' where he gains 5% of his Max Power each time a Buff is Nullified or its Duration expires off the Opponent and Heavy Attacks for Doctor Doom apply up to 1 Armor Break Debuff for 10 seconds, reducing Armor Rating by 15%.

Doctor Doom Synergy with Mister Fantastic
Star | Synergy | Bonus |
---|---|---|
Doctor Doom 3 Star | Nemesis Level 2 | +5% Attack |
Doctor Doom 4 Star | Nemesis Level 3 + Genius Ingenuity | +6% Attack + See Notes |
Doctor Doom 5 Star | Nemesis Level 3 + Genius Ingenuity | +6% Attack + See Notes |

Mister Fantastic Synergy with Doctor Doom
Star | Synergy | Bonus |
---|---|---|
Doctor Doom 3 Star | College Rivals | See Notes |
Doctor Doom 4 Star | College Rivals | See Notes |
Doctor Doom 5 Star | College Rivals | See Notes |
Doctor Doom 6 Star | College Rivals | See Notes |
Mole Man
Add Mole Man to a team with Doctor Doom to activate the 'Fantastic Fiends' synergy bonus so that while Mole Man is Frenzied his attacks lower Defensive Ability Accuracy by 50% when fighting against the #Fantastic Four and Doctor Doom gets a 20% chance to Purify a Debuff. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Mole Man Synergy with Doctor Doom
Star | Synergy | Bonus |
---|---|---|
Doctor Doom 3 Star | Fantastic Fiends | See Notes |
Doctor Doom 4 Star | Fantastic Fiends | See Notes |
Doctor Doom 5 Star | Fantastic Fiends | See Notes |
Platinumpool
Add Platinumpool to a team with Doctor Doom to activate the 'Deathwish' synergy bonus which increases the chance for Platinumpool to draw the Sumopool Card. This is a Solo synergy which does not stack.

Platinumpool Synergy with Doctor Doom
Star | Synergy | Bonus |
---|---|---|
Doctor Doom 5 Star | Deathwish | See Notes |
Doctor Doom 6 Star | Deathwish | See Notes |
Red Skull
Adding Doctor Doom with Red Skull activates the 'Enhanced Forcefield' synergy bonus where Doctor Doom gains +15% Perfect Block chance. Please note this is a solo synergy which does not stack.

Doctor Doom Synergy with Red Skull
Star | Synergy | Bonus |
---|---|---|
Doctor Doom 4 Star | Enhanced Forcefield | See Notes |
Doctor Doom 5 Star | Enhanced Forcefield | See Notes |
Silver Surfer
Add Silver Surfer to a team with Doctor Doom to activate the 'Enemies' synergy bonus, increasing 'Critical Rating' for the whole team.

Silver Surfer Synergy with Doctor Doom
Star | Synergy | Bonus |
---|---|---|
Doctor Doom 3 Star | Enemies Level 1 | +85 Critical Rating |
Doctor Doom 4 Star | Enemies Level 2 | +115 Critical Rating |
Doctor Doom 5 Star | Enemies Level 3 | +155 Critical Rating |
Squirrel Girl
Add Squirrel Girl to a team with Doctor Doom to activate the 'Beat Up the Universe' synergy bonus so that once per fight when Tippy Toe would Purify all non-damaging Debuffs on Squirrel Girl it will also Purify 1 damaging Debuff and Aura of Haazareth for Doctor Doom lasts an additional 2 seconds. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Squirrel Girl Synergy with Doctor Doom
Star | Synergy | Bonus |
---|---|---|
Doctor Doom 5 Star | Beat Up the Universe | See Notes |
Doctor Doom 6 Star | Beat Up the Universe | See Notes |
Symbiote Supreme
Adding Doctor Doom with Symbiote Supreme activates the 'Sorcery Reversal' synergy bonus so when Doctor Doom activates the Aura of Haazareth it has a 50% chance to Purify all Degeneration, Poison, Incinerate, Bleed and Cold Snap Debuffs. Please note this is a solo synergy which does not stack.

Doctor Doom Synergy with Symbiote Supreme
Star | Synergy | Bonus |
---|---|---|
Doctor Doom 4 Star | Sorcery Reversal | See Notes |
Doctor Doom 5 Star | Sorcery Reversal | See Notes |
Thing
Adding Doctor Doom with Thing activates the 'Nemesis' synergy bonus, increasing 'Attack' for the whole team.

Doctor Doom Synergy with Thing
Star | Synergy | Bonus |
---|---|---|
Doctor Doom 3 Star | Nemesis Level 2 | +5% Attack |
Doctor Doom 4 Star | Nemesis Level 3 | +6% Attack |
Doctor Doom 5 Star | Nemesis Level 3 | +6% Attack |