Mister Fantastic Synergy Guide

Add Air-Walker to a team with Mister Fantastic to activate the 'Enemies' synergy bonus, increasing 'Critical Rating' for the whole team.

Adding Mister Fantastic with Angela activates the 'Shared Knowledge - Astronomy' synergy bonus where Cosmic and Skill Champion’s Basic Hits pause one of each Buff on them for 0.2 seconds. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Adding Mister Fantastic with Doctor Octopus activates the 'Shared Knowledge - Robotics' synergy bonus where Tech and Science Champion’s Debuffs also apply an indefinite Power Sting, dealing Direct Damage equal to 60% of their Attack Rating when the Opponent activates a Special Attack. The Power Sting stacks up to 3 times. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Adding Mister Fantastic with Doctor Strange activates the 'Shared Knowledge - Genetics' synergy bonus where Mutant and Mystic Champions regain 5% of the Power spent on any Special Attack, for each unique Special Attack they’ve used in the fight. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Add Dragon Man to a team with Mister Fantastic to activate the 'Student Loans' synergy bonus where Ineptitude reduces the Opponents Armor Rating, Attack Rating, Critical Rating, and Critical Damage Rating for Dragon Man by 10%, and for Mister Fantastic each Careful Study Passive on the Opponent increases his matching Special Attacks damage by 50%. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Add Gamora to a team with Mister Fantastic to activate the 'Cybernetics Upgrade - Assault' synergy bonus where Gamora gains +20% Fury & Cruelty Buff Potency. This is a Solo synergy which does not stack.

Adding Mister Fantastic with Groot activates the 'Shared Knowledge - Astronomy' synergy bonus where Cosmic and Skill Champion’s Basic Hits pause one of each Buff on them for 0.2 seconds. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Add Hulkbuster to a team with Mister Fantastic to activate the 'Engineering Experts' synergy bonus where each Shock Debuff for Hulkbuster reduces the opponent's Offensive Ability Accuracy during Special Attacks by 15% and Mister Fantastic gets +1000 Physical Resistance. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Adding Mister Fantastic with Loki activates the 'Shared Knowledge - Genetics' synergy bonus where Mutant and Mystic Champions regain 5% of the Power spent on any Special Attack, for each unique Special Attack they’ve used in the fight. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Adding Mister Fantastic with Masacre activates the 'Shared Knowledge - Astronomy' synergy bonus where Cosmic and Skill Champion’s Basic Hits pause one of each Buff on them for 0.2 seconds. Please note this is a Unique Synergy which does not stack with duplicate synergies.

A totally unique synergy for Mister Fantastic, 'Council of Reeds' increases Attack Rating by 0% however the potency of this synergy is increased by a flat 30% for each other Mister Fantastic on your team.

Add Mole Man to a team with Mister Fantastic to activate the 'Enemies' synergy bonus, increasing 'Critical Rating' for the whole team.

Adding Mister Fantastic with Night Thrasher activates the 'Shared Knowledge - Astronomy' synergy bonus where Cosmic and Skill Champion’s Basic Hits pause one of each Buff on them for 0.2 seconds. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Adding Mister Fantastic with Psylocke activates the 'Shared Knowledge - Genetics' synergy bonus where Mutant and Mystic Champions regain 5% of the Power spent on any Special Attack, for each unique Special Attack they’ve used in the fight. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Adding Mister Fantastic with Sentry activates the 'Shared Knowledge - Robotics' synergy bonus where Tech and Science Champion’s Debuffs also apply an indefinite Power Sting, dealing Direct Damage equal to 60% of their Attack Rating when the Opponent activates a Special Attack. The Power Sting stacks up to 3 times. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Adding Mister Fantastic with She-Hulk activates the 'Shared Knowledge - Robotics' synergy bonus where Tech and Science Champion’s Debuffs also apply an indefinite Power Sting, dealing Direct Damage equal to 60% of their Attack Rating when the Opponent activates a Special Attack. The Power Sting stacks up to 3 times. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Add Silver Surfer to a team with Mister Fantastic to activate the 'Friends' synergy bonus, increasing 'Armor Rating' for the whole team.

Adding Mister Fantastic with Storm activates the 'Shared Knowledge - Genetics' synergy bonus where Mutant and Mystic Champions regain 5% of the Power spent on any Special Attack, for each unique Special Attack they’ve used in the fight. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Adding Mister Fantastic with Vulture activates the 'Shared Knowledge - Robotics' synergy bonus where Tech and Science Champion’s Debuffs also apply an indefinite Power Sting, dealing Direct Damage equal to 60% of their Attack Rating when the Opponent activates a Special Attack. The Power Sting stacks up to 3 times. Please note this is a Unique Synergy which does not stack with duplicate synergies.