
Mister Fantastic Synergy Guide
Mister Fantastic is a Science class champion in the Contest of Champions who forms a synergy with 23 other characters, available as a 3-Star, 4-Star, 5-Star and 6-Star champion.
Reed Richards is a brilliant scientist, who spearheaded an experimental voyage into space accompanied by his friends and family. An accident occurred during the trip, and the ship was flooded with cosmic rays. After crashing back to Earth, Reed found that he could stretch and elongate his body in impossible ways. He became the leader of the Fantastic Four, and uses his powers of elasticity and his genius intellect to deftly handle all threats, galactic to microscopic.
Synergy Bonuses
Air-Walker
Add Air-Walker to a team with Mister Fantastic to activate the 'Enemies' synergy bonus, increasing 'Critical Rating' for the whole team.
Air-Walker Synergy with Mister Fantastic
Star |
Synergy |
Bonus |
Mister Fantastic 2 Star |
Enemies Level 1 |
+85 Critical Rating |
Mister Fantastic 3 Star |
Enemies Level 2 |
+115 Critical Rating |
Mister Fantastic 4 Star |
Enemies Level 3 |
+155 Critical Rating |
Mister Fantastic 5 Star |
Enemies Level 3 |
+155 Critical Rating |
Mister Fantastic 6 Star |
Enemies Level 3 |
+155 Critical Rating |
Angela
Adding Mister Fantastic with Angela activates the 'Shared Knowledge - Astronomy' synergy bonus where Cosmic and Skill Champion’s Basic Hits pause one of each Buff on them for 0.2 seconds. Please note this is a Unique Synergy which does not stack with duplicate synergies.
Mister Fantastic Synergy with Angela
Star |
Synergy |
Bonus |
Mister Fantastic 3 Star |
Shared Knowledge - Astronomy |
See Notes |
Mister Fantastic 4 Star |
Shared Knowledge - Astronomy |
See Notes |
Mister Fantastic 5 Star |
Shared Knowledge - Astronomy |
See Notes |
Mister Fantastic 6 Star |
Shared Knowledge - Astronomy |
See Notes |
Please note: Mister Fantastic can also activate 'Shared Knowledge - Astronomy' with Groot, Masacre or Night Thrasher as an alternative.
Doctor Doom
Team up Mister Fantatic with the Doctor Doom to activate multiple synergies. Doctor Doom activates the 'Genius Ingenuity' solo synergy (does not stack) where his Shock and Incinerate Debuffs have a +20% increased Potency and in addition he also activates the 'Nemesis' synergy which increases 'Attack' for the whole team. Mister Fantatic activates the unique synergy 'College Rivals' where he gains 5% of his Max Power each time a Buff is Nullified or its Duration expires off the Opponent and Heavy Attacks for Doctor Doom apply up to 1 Armor Break Debuff for 10 seconds, reducing Armor Rating by 15%.
Mister Fantastic Synergy with Doctor Doom
Star |
Synergy |
Bonus |
Mister Fantastic 3 Star |
College Rivals |
See Notes |
Mister Fantastic 4 Star |
College Rivals |
See Notes |
Mister Fantastic 5 Star |
College Rivals |
See Notes |
Mister Fantastic 6 Star |
College Rivals |
See Notes |
Doctor Doom Synergy with Mister Fantastic
Star |
Synergy |
Bonus |
Mister Fantastic 3 Star |
Nemesis Level 2 |
+5% Attack |
Mister Fantastic 4 Star |
Nemesis Level 3 + Genius Ingenuity |
+6% Attack + See Notes |
Mister Fantastic 5 Star |
Nemesis Level 3 + Genius Ingenuity |
+6% Attack + See Notes |
Doctor Octopus
Adding Mister Fantastic with Doctor Octopus activates the 'Shared Knowledge - Robotics' synergy bonus where Tech and Science Champion’s Debuffs also apply an indefinite Power Sting, dealing Direct Damage equal to 60% of their Attack Rating when the Opponent activates a Special Attack. The Power Sting stacks up to 3 times. Please note this is a Unique Synergy which does not stack with duplicate synergies.
Mister Fantastic Synergy with Doctor Octopus
Star |
Synergy |
Bonus |
Mister Fantastic 3 Star |
Shared Knowledge - Robotics |
See Notes |
Mister Fantastic 4 Star |
Shared Knowledge - Robotics |
See Notes |
Mister Fantastic 5 Star |
Shared Knowledge - Robotics |
See Notes |
Mister Fantastic 6 Star |
Shared Knowledge - Robotics |
See Notes |
Please note: Mister Fantastic can also activate 'Shared Knowledge - Robotics' with Sentry, She-Hulk or Vulture as an alternative.
Doctor Strange
Adding Mister Fantastic with Doctor Strange activates the 'Shared Knowledge - Genetics' synergy bonus where Mutant and Mystic Champions regain 5% of the Power spent on any Special Attack, for each unique Special Attack they’ve used in the fight. Please note this is a Unique Synergy which does not stack with duplicate synergies.
Mister Fantastic Synergy with Doctor Strange
Star |
Synergy |
Bonus |
Mister Fantastic 3 Star |
Shared Knowledge - Genetics |
See Notes |
Mister Fantastic 4 Star |
Shared Knowledge - Genetics |
See Notes |
Mister Fantastic 5 Star |
Shared Knowledge - Genetics |
See Notes |
Mister Fantastic 6 Star |
Shared Knowledge - Genetics |
See Notes |
Please note: Mister Fantastic can also activate 'Shared Knowledge - Genetics' with Psylocke, Storm or Loki as an alternative.
Dragon Man
Add Dragon Man to a team with Mister Fantastic to activate the 'Student Loans' synergy bonus where Ineptitude reduces the Opponents Armor Rating, Attack Rating, Critical Rating, and Critical Damage Rating for Dragon Man by 10%, and for Mister Fantastic each Careful Study Passive on the Opponent increases his matching Special Attacks damage by 50%. Please note this is a Unique Synergy which does not stack with duplicate synergies.
Dragon Man Synergy with Mister Fantastic
Star |
Synergy |
Bonus |
Mister Fantastic 4 Star |
Student Loans |
See Notes |
Mister Fantastic 5 Star |
Student Loans |
See Notes |
Mister Fantastic 6 Star |
Student Loans |
See Notes |
Gamora
Add Gamora to a team with Mister Fantastic to activate the 'Cybernetics Upgrade - Assault' synergy bonus where Gamora gains +20% Fury & Cruelty Buff Potency. This is a Solo synergy which does not stack.
Gamora Synergy with Mister Fantastic
Star |
Synergy |
Bonus |
Mister Fantastic 4 Star |
Cybernetics Upgrade - Assault |
See Notes |
Mister Fantastic 6 Star |
Cybernetics Upgrade - Assault |
See Notes |
Groot
Adding Mister Fantastic with Groot activates the 'Shared Knowledge - Astronomy' synergy bonus where Cosmic and Skill Champion’s Basic Hits pause one of each Buff on them for 0.2 seconds. Please note this is a Unique Synergy which does not stack with duplicate synergies.
Mister Fantastic Synergy with Groot
Star |
Synergy |
Bonus |
Mister Fantastic 3 Star |
Shared Knowledge - Astronomy |
See Notes |
Mister Fantastic 4 Star |
Shared Knowledge - Astronomy |
See Notes |
Mister Fantastic 5 Star |
Shared Knowledge - Astronomy |
See Notes |
Mister Fantastic 6 Star |
Shared Knowledge - Astronomy |
See Notes |
Please note: Mister Fantastic can also activate 'Shared Knowledge - Astronomy' with Angela, Masacre or Night Thrasher as an alternative.
Hulkbuster
Add Hulkbuster to a team with Mister Fantastic to activate the 'Engineering Experts' synergy bonus where each Shock Debuff for Hulkbuster reduces the opponent's Offensive Ability Accuracy during Special Attacks by 15% and Mister Fantastic gets +1000 Physical Resistance. Please note this is a Unique Synergy which does not stack with duplicate synergies.
Hulkbuster Synergy with Mister Fantastic
Star |
Synergy |
Bonus |
Mister Fantastic 4 Star |
Engineering Experts |
See Notes |
Mister Fantastic 5 Star |
Engineering Experts |
See Notes |
Mister Fantastic 6 Star |
Engineering Experts |
See Notes |
Human Torch
Team up Mister Fantatic with the Human Torch to activate up to three unique synergies which do not stack. Human Torch activates the 'Rain of Fire' synergy where the last hit of Special Attack 1 Incinerates the Opponent for 6 seconds for other Synergy Members and if all are present it also adds Heal block.
Mister Fantastic activates 'H.E.R.B.I.E.' where Other Synergy Members heal 10% of Max Health over 6 seconds if at or below 20% health at the start of the fight, otherwise gain 60% of a Bar of Power over 6 seconds instead.
If all of the Fantastic Four are in the team the unique synergy is activated where Incinerate and Nova Flame duration is increased by 30% for the Human Torch and for Mister Fantatic with each unique Debuff on the Opponent they take 4% of Mister Fantastic’s current Attack Rating as Direct Damage per second.
Mister Fantastic Synergy with Human Torch
Star |
Synergy |
Bonus |
Mister Fantastic 3 Star |
H.E.R.B.I.E. |
See Notes |
Mister Fantastic 4 Star |
H.E.R.B.I.E. + The Fantastic Four |
See Notes |
Mister Fantastic 5 Star |
H.E.R.B.I.E. + The Fantastic Four |
See Notes |
Mister Fantastic 6 Star |
H.E.R.B.I.E. + The Fantastic Four |
See Notes |
Human Torch Synergy with Mister Fantastic
Star |
Synergy |
Bonus |
Mister Fantastic 3 Star |
Rain of Fire |
See Notes |
Mister Fantastic 4 Star |
Rain of Fire |
See Notes |
Mister Fantastic 5 Star |
Rain of Fire |
See Notes |
Mister Fantastic 6 Star |
Rain of Fire |
See Notes |
Please note: Mister Fantastic can also activate 'H.E.R.B.I.E.' with Thing or Invisible Woman as an alternative. Mister Fantastic can also activate 'The Fantastic Four' with Thing or Invisible Woman as an alternative.
Invisible Woman
Team up Mister Fantatic with the Invisible Woman to activate up to five unique synergies which do not stack. Invisible Woman activates 'Force Block' which increases Block Proficiency by 5% and Perfect Block chance by 10% for other synergy members plus if you’ve teamed all the other Champions in the synergy, then Well-Timed Blocks inflict up to one 10% Weakness Debuff on the Opponent for 6 seconds. The Invisible Woman also activates the 'Till Death…' synergy so that when the Opponent activates a Special Attack, if the Force Field is active, it gains 10% strength for each Bar of Power spent.
Mister Fantastic activates '… Do Us Part' which makes his Debuffs last 25% longer and also 'H.E.R.B.I.E.' where Other Synergy Members heal 10% of Max Health over 6 seconds if at or below 20% health at the start of the fight, otherwise gain 60% of a Bar of Power over 6 seconds instead.
If all of the Fantastic Four are in the team the unique synergy is activated where Invisibility for Invisible Woman only has a 15% chance to unpause during a Well-Timed Block and for Mister Fantatic with each unique Debuff on the Opponent they take 4% of Mister Fantastic’s current Attack Rating as Direct Damage per second.
Mister Fantastic Synergy with Invisible Woman
Star |
Synergy |
Bonus |
Mister Fantastic 3 Star |
H.E.R.B.I.E. + …Do Us Part |
See Notes |
Mister Fantastic 4 Star |
H.E.R.B.I.E. + The Fantastic Four + …Do Us Part |
See Notes |
Mister Fantastic 5 Star |
H.E.R.B.I.E. + The Fantastic Four + …Do Us Part |
See Notes |
Mister Fantastic 6 Star |
H.E.R.B.I.E. + The Fantastic Four + …Do Us Part |
See Notes |
Invisible Woman Synergy with Mister Fantastic
Star |
Synergy |
Bonus |
Mister Fantastic 3 Star |
Force Block + Till Death… |
See Notes |
Mister Fantastic 4 Star |
Force Block + Till Death… |
See Notes |
Mister Fantastic 5 Star |
Force Block + Till Death… |
See Notes |
Mister Fantastic 6 Star |
Force Block + Till Death… |
See Notes |
Please note: Mister Fantastic can also activate 'H.E.R.B.I.E.' with Thing or Human Torch as an alternative. Mister Fantastic can also activate 'The Fantastic Four' with Thing or Human Torch as an alternative.
Loki
Adding Mister Fantastic with Loki activates the 'Shared Knowledge - Genetics' synergy bonus where Mutant and Mystic Champions regain 5% of the Power spent on any Special Attack, for each unique Special Attack they’ve used in the fight. Please note this is a Unique Synergy which does not stack with duplicate synergies.
Mister Fantastic Synergy with Loki
Star |
Synergy |
Bonus |
Mister Fantastic 3 Star |
Shared Knowledge - Genetics |
See Notes |
Mister Fantastic 4 Star |
Shared Knowledge - Genetics |
See Notes |
Mister Fantastic 5 Star |
Shared Knowledge - Genetics |
See Notes |
Mister Fantastic 6 Star |
Shared Knowledge - Genetics |
See Notes |
Please note: Mister Fantastic can also activate 'Shared Knowledge - Genetics' with Psylocke, Storm or Doctor Strange as an alternative.
Masacre
Adding Mister Fantastic with Masacre activates the 'Shared Knowledge - Astronomy' synergy bonus where Cosmic and Skill Champion’s Basic Hits pause one of each Buff on them for 0.2 seconds. Please note this is a Unique Synergy which does not stack with duplicate synergies.
Mister Fantastic Synergy with Masacre
Star |
Synergy |
Bonus |
Mister Fantastic 3 Star |
Shared Knowledge - Astronomy |
See Notes |
Mister Fantastic 4 Star |
Shared Knowledge - Astronomy |
See Notes |
Mister Fantastic 5 Star |
Shared Knowledge - Astronomy |
See Notes |
Mister Fantastic 6 Star |
Shared Knowledge - Astronomy |
See Notes |
Please note: Mister Fantastic can also activate 'Shared Knowledge - Astronomy' with Groot, Angela or Night Thrasher as an alternative.
Mister Fantastic
A totally unique synergy for Mister Fantastic, 'Council of Reeds' increases Attack Rating by 0% however the potency of this synergy is increased by a flat 30% for each other Mister Fantastic on your team.
Mister Fantastic Synergy with Mister Fantastic
Star |
Synergy |
Bonus |
Mister Fantastic 3 Star |
Council of Reeds |
See Notes |
Mister Fantastic 4 Star |
Council of Reeds |
See Notes |
Mister Fantastic 5 Star |
Council of Reeds |
See Notes |
Mister Fantastic 6 Star |
Council of Reeds |
See Notes |
Mole Man
Add Mole Man to a team with Mister Fantastic to activate the 'Enemies' synergy bonus, increasing 'Critical Rating' for the whole team.
Mole Man Synergy with Mister Fantastic
Star |
Synergy |
Bonus |
Mister Fantastic 3 Star |
Enemies Level 1 |
+85 Critical Rating |
Mister Fantastic 4 Star |
Enemies Level 2 |
+115 Critical Rating |
Mister Fantastic 5 Star |
Enemies Level 3 |
+155 Critical Rating |
Night Thrasher
Adding Mister Fantastic with Night Thrasher activates the 'Shared Knowledge - Astronomy' synergy bonus where Cosmic and Skill Champion’s Basic Hits pause one of each Buff on them for 0.2 seconds. Please note this is a Unique Synergy which does not stack with duplicate synergies.
Mister Fantastic Synergy with Night Thrasher
Star |
Synergy |
Bonus |
Mister Fantastic 3 Star |
Shared Knowledge - Astronomy |
See Notes |
Mister Fantastic 4 Star |
Shared Knowledge - Astronomy |
See Notes |
Mister Fantastic 5 Star |
Shared Knowledge - Astronomy |
See Notes |
Mister Fantastic 6 Star |
Shared Knowledge - Astronomy |
See Notes |
Please note: Mister Fantastic can also activate 'Shared Knowledge - Astronomy' with Groot, Angela or Masacre as an alternative.
Psylocke
Adding Mister Fantastic with Psylocke activates the 'Shared Knowledge - Genetics' synergy bonus where Mutant and Mystic Champions regain 5% of the Power spent on any Special Attack, for each unique Special Attack they’ve used in the fight. Please note this is a Unique Synergy which does not stack with duplicate synergies.
Mister Fantastic Synergy with Psylocke
Star |
Synergy |
Bonus |
Mister Fantastic 3 Star |
Shared Knowledge - Genetics |
See Notes |
Mister Fantastic 4 Star |
Shared Knowledge - Genetics |
See Notes |
Mister Fantastic 5 Star |
Shared Knowledge - Genetics |
See Notes |
Mister Fantastic 6 Star |
Shared Knowledge - Genetics |
See Notes |
Please note: Mister Fantastic can also activate 'Shared Knowledge - Genetics' with Storm, Doctor Strange or Loki as an alternative.
Sentry
Adding Mister Fantastic with Sentry activates the 'Shared Knowledge - Robotics' synergy bonus where Tech and Science Champion’s Debuffs also apply an indefinite Power Sting, dealing Direct Damage equal to 60% of their Attack Rating when the Opponent activates a Special Attack. The Power Sting stacks up to 3 times. Please note this is a Unique Synergy which does not stack with duplicate synergies.
Mister Fantastic Synergy with Sentry
Star |
Synergy |
Bonus |
Mister Fantastic 3 Star |
Shared Knowledge - Robotics |
See Notes |
Mister Fantastic 4 Star |
Shared Knowledge - Robotics |
See Notes |
Mister Fantastic 5 Star |
Shared Knowledge - Robotics |
See Notes |
Mister Fantastic 6 Star |
Shared Knowledge - Robotics |
See Notes |
Please note: Mister Fantastic can also activate 'Shared Knowledge - Robotics' with She-Hulk, Vulture or Doctor Octopus as an alternative.
She-Hulk
Adding Mister Fantastic with She-Hulk activates the 'Shared Knowledge - Robotics' synergy bonus where Tech and Science Champion’s Debuffs also apply an indefinite Power Sting, dealing Direct Damage equal to 60% of their Attack Rating when the Opponent activates a Special Attack. The Power Sting stacks up to 3 times. Please note this is a Unique Synergy which does not stack with duplicate synergies.
Mister Fantastic Synergy with She-Hulk
Star |
Synergy |
Bonus |
Mister Fantastic 3 Star |
Shared Knowledge - Robotics |
See Notes |
Mister Fantastic 4 Star |
Shared Knowledge - Robotics |
See Notes |
Mister Fantastic 5 Star |
Shared Knowledge - Robotics |
See Notes |
Mister Fantastic 6 Star |
Shared Knowledge - Robotics |
See Notes |
Please note: Mister Fantastic can also activate 'Shared Knowledge - Robotics' with Sentry, Vulture or Doctor Octopus as an alternative.
Silver Surfer
Add Silver Surfer to a team with Mister Fantastic to activate the 'Friends' synergy bonus, increasing 'Armor Rating' for the whole team.
Silver Surfer Synergy with Mister Fantastic
Star |
Synergy |
Bonus |
Mister Fantastic 3 Star |
Friends Level 1 |
+70 Armor Rating |
Mister Fantastic 4 Star |
Friends Level 2 |
+95 Armor Rating |
Mister Fantastic 5 Star |
Friends Level 3 |
+130 Armor Rating |
Storm
Adding Mister Fantastic with Storm activates the 'Shared Knowledge - Genetics' synergy bonus where Mutant and Mystic Champions regain 5% of the Power spent on any Special Attack, for each unique Special Attack they’ve used in the fight. Please note this is a Unique Synergy which does not stack with duplicate synergies.
Mister Fantastic Synergy with Storm
Star |
Synergy |
Bonus |
Mister Fantastic 3 Star |
Shared Knowledge - Genetics |
See Notes |
Mister Fantastic 4 Star |
Shared Knowledge - Genetics |
See Notes |
Mister Fantastic 5 Star |
Shared Knowledge - Genetics |
See Notes |
Mister Fantastic 6 Star |
Shared Knowledge - Genetics |
See Notes |
Please note: Mister Fantastic can also activate 'Shared Knowledge - Genetics' with Psylocke, Doctor Strange or Loki as an alternative.
Thing
Team up Mister Fantatic with the Thing to activate up to three unique synergies which do not stack. Thing activates the 'The Brave and the Boulder' which makes where the last hit of Special Attack 2 for other Synergy Members grant a Fury Buff for 6 seconds, increasing Attack by 15% of Base Attack which is doubled if all Champions of the Synergy are present.
Mister Fantastic activates 'H.E.R.B.I.E.' where Other Synergy Members heal 10% of Max Health over 6 seconds if at or below 20% health at the start of the fight, otherwise gain 60% of a Bar of Power over 6 seconds instead.
If all of the Fantastic Four are in the team the unique synergy is activated so that whenever Thing would gain a Rock Stack he gains an additional one and for Mister Fantatic with each unique Debuff on the Opponent they take 4% of Mister Fantastic’s current Attack Rating as Direct Damage per second.
Mister Fantastic Synergy with Thing
Star |
Synergy |
Bonus |
Mister Fantastic 3 Star |
H.E.R.B.I.E. |
See Notes |
Mister Fantastic 4 Star |
H.E.R.B.I.E. + The Fantastic Four |
See Notes |
Mister Fantastic 5 Star |
H.E.R.B.I.E. + The Fantastic Four |
See Notes |
Mister Fantastic 6 Star |
H.E.R.B.I.E. + The Fantastic Four |
See Notes |
Thing Synergy with Mister Fantastic
Star |
Synergy |
Bonus |
Mister Fantastic 2 Star |
The Brave and the Boulder |
See Notes |
Mister Fantastic 3 Star |
The Brave and the Boulder |
See Notes |
Mister Fantastic 4 Star |
The Brave and the Boulder |
See Notes |
Mister Fantastic 5 Star |
The Brave and the Boulder |
See Notes |
Mister Fantastic 6 Star |
The Brave and the Boulder |
See Notes |
Please note: Mister Fantastic can also activate 'H.E.R.B.I.E.' with Human Torch or Invisible Woman as an alternative. Mister Fantastic can also activate 'The Fantastic Four' with Human Torch or Invisible Woman as an alternative.
Vulture
Adding Mister Fantastic with Vulture activates the 'Shared Knowledge - Robotics' synergy bonus where Tech and Science Champion’s Debuffs also apply an indefinite Power Sting, dealing Direct Damage equal to 60% of their Attack Rating when the Opponent activates a Special Attack. The Power Sting stacks up to 3 times. Please note this is a Unique Synergy which does not stack with duplicate synergies.
Mister Fantastic Synergy with Vulture
Star |
Synergy |
Bonus |
Mister Fantastic 3 Star |
Shared Knowledge - Robotics |
See Notes |
Mister Fantastic 4 Star |
Shared Knowledge - Robotics |
See Notes |
Mister Fantastic 5 Star |
Shared Knowledge - Robotics |
See Notes |
Mister Fantastic 6 Star |
Shared Knowledge - Robotics |
See Notes |
Please note: Mister Fantastic can also activate 'Shared Knowledge - Robotics' with Sentry, She-Hulk or Doctor Octopus as an alternative.