Doctor Octopus Synergy Guide
Doctor Octopus is a Tech class villain champion in the Contest of Champions who forms a synergy with 7 other characters, available as a 2-Star, 3-Star, 4-Star, 5-Star and 6-Star champion.
Otton Octavius came from a troubled home. Determined not to follow in his abusive father's footsteps, Otto devoted himself to his studies. Despite years of derision from his peers, he became a nuclear physicist. But after he had to have the mechanical arms he designed and built surgically removed following an accident Otto finally had enough. Assuming the derogatory name his co-workers had coined for him, Otto began a life of crime as Doctor Octopus.
Adding Doctor Octopus with Ant-Man activates the 'Biochemistry' synergy bonus where Doctor Octopus gets to start the fight with 40 Chemistry Research whilst Ant-Man reflects 40% of Physical Damage done by attacks that make contact with his Glancing Hits.
|Doctor Octopus 3 Star||Biochemistry||See Notes|
|Doctor Octopus 4 Star||Biochemistry||See Notes|
|Doctor Octopus 5 Star||Biochemistry||See Notes|
|Doctor Octopus 6 Star||Biochemistry||See Notes|
Add Diablo to a team with Doctor Octopus to activate the 'Madcap Experimentalists' synergy bonus where Diablo gets to recover 1 Lifestitch after winning 1 Fight and Doctor Octopus gets +30% Heal Block Debuff duration. Please note this is a Unique Synergy which does not stack with duplicate synergies.
|Diablo 3 Star||Madcap Experimentalists||See Notes|
|Diablo 4 Star||Madcap Experimentalists||See Notes|
|Diablo 5 Star||Madcap Experimentalists||See Notes|
|Diablo 6 Star||Madcap Experimentalists||See Notes|
Adding Doctor Octopus with Electro activates the 'Particle Physics' synergy bonus where Doctor Octopus has his Research Categories reset to 50 when a Breakthrough expires and Electro gains 50% additional Power from Critical Hits
|Doctor Octopus 2 Star||Particle Physics||See Notes|
|Doctor Octopus 3 Star||Particle Physics||See Notes|
|Doctor Octopus 4 Star||Particle Physics||See Notes|
|Doctor Octopus 5 Star||Particle Physics||See Notes|
|Doctor Octopus 6 Star||Particle Physics||See Notes|
|M.O.D.O.K. 3 Star||Masterminds Level 1||+10% Attack|
|M.O.D.O.K. 4 Star||Masterminds Level 2||+12% Attack|
|M.O.D.O.K. 5 Star||Masterminds Level 2||+12% Attack|
|M.O.D.O.K. 6 Star||Masterminds Level 2||+12% Attack|
Spider-Man (Stark Enhanced)
|Doctor Octopus 4 Star||Nemesis Level 3||+6% Attack|
|Doctor Octopus 5 Star||Nemesis Level 3||+6% Attack|
|Doctor Octopus 6 Star||Nemesis Level 3||+6% Attack|
|Venom 3 Star||Rivals Level 2||+90 Critical Damage Rating|
|Venom 4 Star||Rivals Level 3||+115 Critical Damage Rating|
|Venom 5 Star||Rivals Level 3||+115 Critical Damage Rating|
Adding Doctor Octopus with Vulture activates the 'Engineering' synergy bonus where Research Categories for Doctor Octopus no longer fall off over time and Vulture gains an additional +5 Chitauri Charge on a Critical Hit.
|Doctor Octopus 4 Star||Engineering||See Notes|
|Doctor Octopus 5 Star||Engineering||See Notes|
|Doctor Octopus 6 Star||Engineering||See Notes|