Diablo Synergy Guide

Diablo is a Mystic class champion in the Contest of Champions who forms a synergy with 9 other characters, available as a 3-Star, 4-Star, 5-Star and 6-Star champion.

An unrivalled alchemist and a member of Spanish nobility, Esteban Corazon de Ablo uses his arcane concoctions to lengthen his life, incinerate his foes and more. Driven by an unending desire to become as powerful as a god, Diablo now finds himself in the Contest hoping to secure the ISO-Sphere for his continued experimentation. Ambition pushes the Spanish nobleman to acquire power at all costs, and very few heroes can, or will, stand in his way.

Synergy Bonuses

'Unending Ambition' with Loki or Red Skull
'Madcap Experimentalists' with Doctor Octopus or Green Goblin
'Nemesis' with Thing
'Twisted Arcanists' with Symbiote Supreme or Dormammu
'Legion Accursed' with Mephisto or Juggernaut

Doctor Octopus

Adding Diablo with Doctor Octopus activates the 'Madcap Experimentalists' synergy bonus where Diablo gets to recover 1 Lifestitch after winning 1 Fight and Doctor Octopus gets +30% Heal Block Debuff duration. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Diablo Synergy with Doctor Octopus

Star	Synergy	Bonus
Diablo 3 Star	Madcap Experimentalists	See Notes
Diablo 4 Star	Madcap Experimentalists	See Notes
Diablo 5 Star	Madcap Experimentalists	See Notes
Diablo 6 Star	Madcap Experimentalists	See Notes

Please note: Diablo can also activate 'Madcap Experimentalists' with Green Goblin as an alternative.

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Dormammu

Adding Diablo with Dormammu activates the 'Twisted Arcanists' synergy bonus where Diablo gets to recover 1 Emberboon after winning 1 Fight and Dormammu gets +500 Energy Resistance while Dark Energy is at 100. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Diablo Synergy with Dormammu

Star	Synergy	Bonus
Diablo 4 Star	Twisted Arcanists	See Notes
Diablo 5 Star	Twisted Arcanists	See Notes
Diablo 6 Star	Twisted Arcanists	See Notes

Please note: Diablo can also activate 'Twisted Arcanists' with Symbiote Supreme as an alternative.

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Green Goblin

Adding Diablo with Green Goblin activates the 'Madcap Experimentalists' synergy bonus where Diablo gets to recover 1 Lifestitch after winning 1 Fight and Green Goblin gets +1% Attack per Cunning / Madness charge. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Diablo Synergy with Green Goblin

Star	Synergy	Bonus
Diablo 3 Star	Madcap Experimentalists	See Notes
Diablo 4 Star	Madcap Experimentalists	See Notes
Diablo 5 Star	Madcap Experimentalists	See Notes
Diablo 6 Star	Madcap Experimentalists	See Notes

Please note: Diablo can also activate 'Madcap Experimentalists' with Doctor Octopus as an alternative.

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Juggernaut

Adding Diablo with Juggernaut activates the 'Legion Accursed' synergy bonus where Diablo gets to recover 1 Ironskin after winning 1 Fight and Juggernaut gets +2000 Armor during Heavy Attacks. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Diablo Synergy with Juggernaut

Star	Synergy	Bonus
Diablo 4 Star	Legion Accursed	See Notes
Diablo 5 Star	Legion Accursed	See Notes
Diablo 6 Star	Legion Accursed	See Notes

Please note: Diablo can also activate 'Legion Accursed' with Mephisto as an alternative.

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Loki

Adding Diablo with Loki activates the 'Unending Ambition' synergy bonus where Diablo gets to recover 1 Counterflow after winning 1 Fight and Loki gets +35% Curse Debuff duration. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Diablo Synergy with Loki

Star	Synergy	Bonus
Diablo 3 Star	Unending Ambition	See Notes
Diablo 4 Star	Unending Ambition	See Notes
Diablo 5 Star	Unending Ambition	See Notes
Diablo 6 Star	Unending Ambition	See Notes

Please note: Diablo can also activate 'Unending Ambition' with Red Skull as an alternative.

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Mephisto

Adding Diablo with Mephisto activates the 'Legion Accursed' synergy bonus where Diablo gets to recover 1 Ironskin after winning 1 Fight and Mephisto gains 40% of a Power bar when a Poison Debuff would be gained. Cooldown 10 seconds. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Diablo Synergy with Mephisto

Star	Synergy	Bonus
Diablo 4 Star	Legion Accursed	See Notes
Diablo 5 Star	Legion Accursed	See Notes
Diablo 6 Star	Legion Accursed	See Notes

Please note: Diablo can also activate 'Legion Accursed' with Juggernaut as an alternative.

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Red Skull

Adding Diablo with Red Skull activates the 'Unending Ambition' synergy bonus where Diablo gets to recover 1 Counterflow after winning 1 Fight and Red Skull gets +35% Shock Debuff Damage. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Diablo Synergy with Red Skull

Star	Synergy	Bonus
Diablo 3 Star	Unending Ambition	See Notes
Diablo 4 Star	Unending Ambition	See Notes
Diablo 5 Star	Unending Ambition	See Notes
Diablo 6 Star	Unending Ambition	See Notes

Please note: Diablo can also activate 'Unending Ambition' with Loki as an alternative.

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Symbiote Supreme

Adding Diablo with Symbiote Supreme activates the 'Twisted Arcanists' synergy bonus where Diablo gets to recover 1 Emberboon after winning 1 Fight and Symbiote Supreme gets +1% Attack per for each Stagger on the opponent. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Diablo Synergy with Symbiote Supreme

Star	Synergy	Bonus
Diablo 4 Star	Twisted Arcanists	See Notes
Diablo 5 Star	Twisted Arcanists	See Notes
Diablo 6 Star	Twisted Arcanists	See Notes

Please note: Diablo can also activate 'Twisted Arcanists' with Dormammu as an alternative.

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Thing

Adding Diablo with Thing activates the 'Nemesis' synergy bonus, increasing 'Attack' for the whole team.

Diablo Synergy with Thing

Star	Synergy	Bonus
Diablo 3 Star	Nemesis Level 2	+5% Attack
Diablo 4 Star	Nemesis Level 3	+6% Attack
Diablo 5 Star	Nemesis Level 3	+6% Attack
Diablo 6 Star	Nemesis Level 3	+6% Attack

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