
Diablo Synergy Guide
Diablo is a Mystic class champion in the Contest of Champions who forms a synergy with 12 other characters, available as a 3-Star, 4-Star, 5-Star and 6-Star champion.
An unrivalled alchemist and a member of Spanish nobility, Esteban Corazon de Ablo uses his arcane concoctions to lengthen his life, incinerate his foes and more. Driven by an unending desire to become as powerful as a god, Diablo now finds himself in the Contest hoping to secure the ISO-Sphere for his continued experimentation. Ambition pushes the Spanish nobleman to acquire power at all costs, and very few heroes can, or will, stand in his way.
Synergy Bonuses
- 'Unending Ambition' with Loki or Red Skull
- 'Madcap Experimentalists' with Doctor Octopus or Green Goblin
- 'Nemesis' with Thing
- 'Twisted Arcanists' with Symbiote Supreme or Dormammu
- 'Legion Accursed' with Mephisto or Juggernaut

Doctor Doom
Add Doctor Doom to a team with Diablo to activate the 'Fantastic Rage' synergy bonus where Heavy Attacks for Doctor Doom are guaranteed critical hits while the Opponent is suffering from a Stagger effect. Please note this is a solo synergy which does not stack.

Doctor Doom Synergy with Diablo
Star | Synergy | Bonus |
---|---|---|
Diablo 4 Star | Fantastic Rage | See Notes |
Diablo 5 Star | Fantastic Rage | See Notes |
Doctor Octopus
Adding Diablo with Doctor Octopus activates the 'Madcap Experimentalists' synergy bonus where Diablo gets to recover 1 Lifestitch after winning 1 Fight and Doctor Octopus gets +30% Heal Block Debuff duration. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Diablo Synergy with Doctor Octopus
Star | Synergy | Bonus |
---|---|---|
Diablo 3 Star | Madcap Experimentalists | See Notes |
Diablo 4 Star | Madcap Experimentalists | See Notes |
Diablo 5 Star | Madcap Experimentalists | See Notes |
Diablo 6 Star | Madcap Experimentalists | See Notes |
Dormammu
Adding Diablo with Dormammu activates the 'Twisted Arcanists' synergy bonus where Diablo gets to recover 1 Emberboon after winning 1 Fight and Dormammu gets +500 Energy Resistance while Dark Energy is at 100. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Diablo Synergy with Dormammu
Star | Synergy | Bonus |
---|---|---|
Diablo 4 Star | Twisted Arcanists | See Notes |
Diablo 5 Star | Twisted Arcanists | See Notes |
Diablo 6 Star | Twisted Arcanists | See Notes |
Dragon Man
Add Dragon Man to a team with Diablo to activate the 'Full Metal' synergy bonus where Special 3 for Dragon Man generates an additional stack of Power Charge, and Diablo can now instantly consume Concoctions after they’ve been brewed, plus his Concoctions have a 50% chance to be recovered after brewing. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Dragon Man Synergy with Diablo
Star | Synergy | Bonus |
---|---|---|
Diablo 4 Star | Full Metal | See Notes |
Diablo 5 Star | Full Metal | See Notes |
Diablo 6 Star | Full Metal | See Notes |
Green Goblin
Adding Diablo with Green Goblin activates the 'Madcap Experimentalists' synergy bonus where Diablo gets to recover 1 Lifestitch after winning 1 Fight and Green Goblin gets +1% Attack per Cunning / Madness charge. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Diablo Synergy with Green Goblin
Star | Synergy | Bonus |
---|---|---|
Diablo 3 Star | Madcap Experimentalists | See Notes |
Diablo 4 Star | Madcap Experimentalists | See Notes |
Diablo 5 Star | Madcap Experimentalists | See Notes |
Diablo 6 Star | Madcap Experimentalists | See Notes |
Juggernaut
Adding Diablo with Juggernaut activates the 'Legion Accursed' synergy bonus where Diablo gets to recover 1 Ironskin after winning 1 Fight and Juggernaut gets +2000 Armor during Heavy Attacks. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Diablo Synergy with Juggernaut
Star | Synergy | Bonus |
---|---|---|
Diablo 4 Star | Legion Accursed | See Notes |
Diablo 5 Star | Legion Accursed | See Notes |
Diablo 6 Star | Legion Accursed | See Notes |
Loki
Adding Diablo with Loki activates the 'Unending Ambition' synergy bonus where Diablo gets to recover 1 Counterflow after winning 1 Fight and Loki gets +35% Curse Debuff duration. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Diablo Synergy with Loki
Star | Synergy | Bonus |
---|---|---|
Diablo 3 Star | Unending Ambition | See Notes |
Diablo 4 Star | Unending Ambition | See Notes |
Diablo 5 Star | Unending Ambition | See Notes |
Diablo 6 Star | Unending Ambition | See Notes |
Mephisto
Adding Diablo with Mephisto activates the 'Legion Accursed' synergy bonus where Diablo gets to recover 1 Ironskin after winning 1 Fight and Mephisto gains 40% of a Power bar when a Poison Debuff would be gained. Cooldown 10 seconds. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Diablo Synergy with Mephisto
Star | Synergy | Bonus |
---|---|---|
Diablo 4 Star | Legion Accursed | See Notes |
Diablo 5 Star | Legion Accursed | See Notes |
Diablo 6 Star | Legion Accursed | See Notes |
Mole Man
Add Mole Man to a team with Diablo to activate the 'Fantastic Fiends' synergy bonus so that while Mole Man is Frenzied his attacks lower Defensive Ability Accuracy by 50% when fighting against the #Fantastic Four and Diablo gets a 20% chance to Purify a Debuff. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Mole Man Synergy with Diablo
Star | Synergy | Bonus |
---|---|---|
Diablo 3 Star | Fantastic Fiends | See Notes |
Diablo 4 Star | Fantastic Fiends | See Notes |
Diablo 5 Star | Fantastic Fiends | See Notes |
Red Skull
Adding Diablo with Red Skull activates the 'Unending Ambition' synergy bonus where Diablo gets to recover 1 Counterflow after winning 1 Fight and Red Skull gets +35% Shock Debuff Damage. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Diablo Synergy with Red Skull
Star | Synergy | Bonus |
---|---|---|
Diablo 3 Star | Unending Ambition | See Notes |
Diablo 4 Star | Unending Ambition | See Notes |
Diablo 5 Star | Unending Ambition | See Notes |
Diablo 6 Star | Unending Ambition | See Notes |
Symbiote Supreme
Adding Diablo with Symbiote Supreme activates the 'Twisted Arcanists' synergy bonus where Diablo gets to recover 1 Emberboon after winning 1 Fight and Symbiote Supreme gets +1% Attack per for each Stagger on the opponent. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Diablo Synergy with Symbiote Supreme
Star | Synergy | Bonus |
---|---|---|
Diablo 4 Star | Twisted Arcanists | See Notes |
Diablo 5 Star | Twisted Arcanists | See Notes |
Diablo 6 Star | Twisted Arcanists | See Notes |
Thing
Adding Diablo with Thing activates the 'Nemesis' synergy bonus, increasing 'Attack' for the whole team.

Diablo Synergy with Thing
Star | Synergy | Bonus |
---|---|---|
Diablo 3 Star | Nemesis Level 2 | +5% Attack |
Diablo 4 Star | Nemesis Level 3 | +6% Attack |
Diablo 5 Star | Nemesis Level 3 | +6% Attack |
Diablo 6 Star | Nemesis Level 3 | +6% Attack |