
Doctor Strange Synergy Guide
Doctor Strange is a Mystic class champion in the Contest of Champions who forms a synergy with 27 other characters, available as a 2-Star, 3-Star and 4-Star champion.
Neurosurgeon Doctor Stephen Strange's success caused him to hit rock bottom. But the Ancient One elevated him to new heights, as Doctor Strange, Sorcerer Supreme! He is the Master of the Mystic Arts, with powerful magic spells at his command. But forget the Flames of the Faltime, the Cloak of Levitation, the eye of Agamotto – behind all that is a tenacious warrior dedicated to defending the Earth against the darkest mystical adversaries!
Synergy Bonuses
- 'Friends' with Thor or Wolverine X-23
- 'Friends' with Spider-Man (Classic)
- 'Teammates' with Scarlet Witch (Classic)
- 'Teammates' with Black Bolt

Bishop
Add Bishop to a team with Doctor Strange to activate the 'Energy Conduit' synergy bonus where Bishop gets to start the fight with +1 Prowess and 4% Power at Level 1, or +2 Prowess and 8% Power at Level 2 and Doctor Strange gets a 3% Energy Resistance Level 1, or 8% Energy Resistance at Level 2.

Bishop Synergy with Doctor Strange
Star | Synergy | Bonus |
---|---|---|
Doctor Strange 3 Star | Energy Conduit Level 1 | See Notes |
Doctor Strange 4 Star | Energy Conduit Level 2 | See Notes |
Doctor Strange 5 Star | Energy Conduit Level 2 | See Notes |
Doctor Strange 6 Star | Energy Conduit Level 2 | See Notes |
Black Bolt
Adding Doctor Strange with Black Bolt activates the 'Teammates' synergy bonus, increasing 'Perfect Block' for the whole team.

Doctor Strange Synergy with Black Bolt
Star | Synergy | Bonus |
---|---|---|
Doctor Strange 3 Star | Teammates Level 2 | +4% Perfect Block |
Doctor Strange 4 Star | Teammates Level 3 | +5% Perfect Block |
Black Widow (Claire Voyant)
Add Black Widow (Claire Voyant) to a team with Doctor Strange to activate the 'A Spell A Day Keeps The Doctor Away' synergy bonus where the final hit of Special 2 for Black Widow (Claire Voyant) and Doctor Strange has a 50% chance to inflict Stun for 2 seconds.

Black Widow (Claire Voyant) Synergy with Doctor Strange
Star | Synergy | Bonus |
---|---|---|
Doctor Strange 4 Star | A Spell A Day Keeps The Doctor Away | See Notes |
Doctor Strange 5 Star | A Spell A Day Keeps The Doctor Away | See Notes |
Captain America (Infinity War)
Add Captain America (Infinity War) to a team with Doctor Strange to activate the 'Mystic Craft' synergy bonus where the Mystic Champions on your team deal 30% of their attack as Direct Damage to their Opponent when Nullifying one of their Buffs. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Captain America (Infinity War) Synergy with Doctor Strange
Star | Synergy | Bonus |
---|---|---|
Doctor Strange 3 Star | Mystic Craft | See Notes |
Doctor Strange 4 Star | Mystic Craft | See Notes |
Doctor Strange 5 Star | Mystic Craft | See Notes |
Doctor Strange 6 Star | Mystic Craft | See Notes |
Corvus Glaive
Add Corvus Glaive to a team with Doctor Strange to activate the 'Infinity Enemies' synergy bonus, increasing 'Attack' for the whole team.

Corvus Glaive Synergy with Doctor Strange
Star | Synergy | Bonus |
---|---|---|
Doctor Strange 3 Star | Infinity Enemies Level 2 | +5% Attack |
Doctor Strange 4 Star | Infinity Enemies Level 4 | +6% Attack |
Doctor Strange 5 Star | Infinity Enemies Level 4 | +6% Attack |
Doctor Strange 6 Star | Infinity Enemies Level 4 | +6% Attack |
Cull Obsidian
Add Cull Obsidian to a team with Doctor Strange to activate the 'Enemies' synergy bonus, increasing 'Critical Rating' for the whole team.

Cull Obsidian Synergy with Doctor Strange
Star | Synergy | Bonus |
---|---|---|
Doctor Strange 3 Star | Enemies Level 2 | +115 Critical Rating |
Doctor Strange 4 Star | Enemies Level 3 | +155 Critical Rating |
Doctor Strange 5 Star | Enemies Level 3 | +155 Critical Rating |
Doctor Doom
Add Doctor Doom to a team with Doctor Strange to activate the 'Sorcery Reversal' synergy bonus so when Doctor Doom activates the Aura of Haazareth it has a 50% chance to Purify all Degeneration, Poison, Incinerate, Bleed and Cold Snap Debuffs. Please note this is a solo synergy which does not stack.

Doctor Doom Synergy with Doctor Strange
Star | Synergy | Bonus |
---|---|---|
Doctor Strange 4 Star | Sorcery Reversal | See Notes |
Doctor Strange 5 Star | Sorcery Reversal | See Notes |
Doctor Voodoo
Add Doctor Voodoo to a team with Doctor Strange to activate the 'Rivals' synergy bonus, increasing 'Critical Damage Rating' for the whole team.

Doctor Voodoo Synergy with Doctor Strange
Star | Synergy | Bonus |
---|---|---|
Doctor Strange 3 Star | Rivals Level 2 | +90 Critical Damage Rating |
Doctor Strange 4 Star | Rivals Level 3 | +115 Critical Damage Rating |
Doctor Strange 5 Star | Rivals Level 3 | +115 Critical Damage Rating |
Dormammu
Add Dormammu to a team with Doctor Strange to activate the 'Nemesis' synergy bonus, increasing 'Attack' for the whole team.

Dormammu Synergy with Doctor Strange
Star | Synergy | Bonus |
---|---|---|
Doctor Strange 2 Star | Nemesis Level 1 | +4% Attack |
Doctor Strange 3 Star | Nemesis Level 2 | +5% Attack |
Doctor Strange 4 Star | Nemesis Level 3 | +6% Attack |
Doctor Strange 5 Star | Nemesis Level 3 | +6% Attack |
Doctor Strange 6 Star | Nemesis Level 3 | +6% Attack |
Ebony Maw
Add Ebony Maw to a team with Doctor Strange to activate the 'Enemies' synergy bonus, increasing 'Critical Rating' for the whole team.

Ebony Maw Synergy with Doctor Strange
Star | Synergy | Bonus |
---|---|---|
Doctor Strange 3 Star | Enemies Level 2 | +115 Critical Rating |
Doctor Strange 4 Star | Enemies Level 3 | +155 Critical Rating |
Doctor Strange 5 Star | Enemies Level 3 | +155 Critical Rating |
Hyperion
Add Hyperion to a team with Doctor Strange to activate the 'Enemies' synergy bonus, increasing 'Critical Rating' for the whole team.

Hyperion Synergy with Doctor Strange
Star | Synergy | Bonus |
---|---|---|
Doctor Strange 4 Star | Enemies Level 3 | +155 Critical Rating |
Doctor Strange 5 Star | Enemies Level 3 | +155 Critical Rating |
Iron Fist
Add Iron Fist to a team with Doctor Strange to activate the 'Friends' synergy bonus, increasing 'Armor Rating' for the whole team.

Iron Fist Synergy with Doctor Strange
Star | Synergy | Bonus |
---|---|---|
Doctor Strange 3 Star | Friends Level 2 | +95 Armor Rating |
Doctor Strange 4 Star | Friends Level 3 | +130 Armor Rating |
Doctor Strange 5 Star | Friends Level 3 | +130 Armor Rating |
Doctor Strange 6 Star | Friends Level 3 | +130 Armor Rating |
Iron Fist (Immortal)
Add Iron Fist (Immortal) to a team with Doctor Strange to activate the 'Friends' synergy bonus, increasing 'Armor Rating' for the whole team.

Iron Fist (Immortal) Synergy with Doctor Strange
Star | Synergy | Bonus |
---|---|---|
Doctor Strange 4 Star | Friends Level 3 | +130 Armor Rating |
Doctor Strange 5 Star | Friends Level 3 | +130 Armor Rating |
Juggernaut
Add Juggernaut to a team with Doctor Strange to activate the 'Nemesis' synergy bonus, increasing 'Attack' for the whole team.

Juggernaut Synergy with Doctor Strange
Star | Synergy | Bonus |
---|---|---|
Doctor Strange 3 Star | Nemesis Level 1 | +4% Attack |
Doctor Strange 4 Star | Nemesis Level 2 | +5% Attack |
Doctor Strange 5 Star | Nemesis Level 2 | +5% Attack |
Doctor Strange 6 Star | Nemesis Level 2 | +5% Attack |
Mephisto
Add Mephisto to a team with Doctor Strange to activate the 'Pact with a Demon' synergy bonus where Doctor Strange heals an additional 70% with Life Steal and Mephisto gets +70% Incinerate Energy Damage. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Mephisto Synergy with Doctor Strange
Star | Synergy | Bonus |
---|---|---|
Doctor Strange 3 Star | Pact with a Demon | See Notes |
Doctor Strange 4 Star | Pact with a Demon | See Notes |
Doctor Strange 5 Star | Pact with a Demon | See Notes |
Mister Fantastic
Add Mister Fantastic to a team with Doctor Strange to activate the 'Shared Knowledge - Genetics' synergy bonus where Mutant and Mystic Champions regain 5% of the Power spent on any Special Attack, for each unique Special Attack they’ve used in the fight. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Mister Fantastic Synergy with Doctor Strange
Star | Synergy | Bonus |
---|---|---|
Doctor Strange 3 Star | Shared Knowledge - Genetics | See Notes |
Doctor Strange 4 Star | Shared Knowledge - Genetics | See Notes |
Doctor Strange 5 Star | Shared Knowledge - Genetics | See Notes |
Doctor Strange 6 Star | Shared Knowledge - Genetics | See Notes |
Mordo
Add Mordo to a team with Doctor Strange to activate the 'Rivals' synergy bonus, increasing 'Critical Damage Rating' for the whole team. In addition Mordo activates the 'Friends' synergy bonus, increasing 'Armor' for all champions in the team.

Mordo Synergy with Doctor Strange
Star | Synergy | Bonus |
---|---|---|
Doctor Strange 2 Star | Friends Level 1 | +70 Armor Rating |
Doctor Strange 3 Star | Friends Level 2 + Rivals Level 2 | +95 Armor Rating + +90 Critical Damage Rating |
Doctor Strange 4 Star | Friends Level 3 + Rivals Level 3 | +130 Armor Rating + +115 Critical Damage Rating |
Doctor Strange 5 Star | Friends Level 3 + Rivals Level 3 | +130 Armor Rating + +115 Critical Damage Rating |
Proxima Midnight
Add Proxima Midnight to a team with Doctor Strange to activate the 'Infinity Enemies' synergy bonus, increasing 'Attack' for the whole team.

Proxima Midnight Synergy with Doctor Strange
Star | Synergy | Bonus |
---|---|---|
Doctor Strange 3 Star | Infinity Enemies Level 2 | +5% Attack |
Doctor Strange 4 Star | Infinity Enemies Level 4 | +6% Attack |
Doctor Strange 5 Star | Infinity Enemies Level 4 | +6% Attack |
Scarlet Witch (Classic)
Adding Doctor Strange with Scarlet Witch (Classic) activates the 'Teammates' synergy bonus, increasing 'Perfect Block' for the whole team.

Doctor Strange Synergy with Scarlet Witch (Classic)
Star | Synergy | Bonus |
---|---|---|
Doctor Strange 2 Star | Teammates Level 1 | +3% Perfect Block |
Doctor Strange 3 Star | Teammates Level 2 | +4% Perfect Block |
Doctor Strange 4 Star | Teammates Level 3 | +5% Perfect Block |
Silver Surfer
Add Silver Surfer to a team with Doctor Strange to activate the 'Secret Defenders' synergy bonus which reduces the cooldown of Silver Surfer’s Power Cosmic Buff by 3.0 seconds whilst it increases the Potency of each of Doctor Strange’s Blessings by 25%. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Silver Surfer Synergy with Doctor Strange
Star | Synergy | Bonus |
---|---|---|
Doctor Strange 3 Star | Secret Defenders | See Notes |
Doctor Strange 4 Star | Secret Defenders | See Notes |
Doctor Strange 5 Star | Secret Defenders | See Notes |
Sorcerer Supreme
Add Sorcerer Supreme to a team with Doctor Strange to activate the 'Doctors Strange' synergy bonus where Sorcerer Supreme and Doctor Strange gain Passive Prowess whenever a Blessing activates (capped at 3), increasing Special Attack damage by 15% which lasts until the end of their next Special Attack. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Sorcerer Supreme Synergy with Doctor Strange
Star | Synergy | Bonus |
---|---|---|
Doctor Strange 5 Star | Doctors Strange | See Notes |
Doctor Strange 6 Star | Doctors Strange | See Notes |
Spider-Man (Classic)
Adding Doctor Strange with Spider-Man (Classic) activates the 'Friends' synergy bonus, increasing 'Armor Rating' for the whole team.

Doctor Strange Synergy with Spider-Man (Classic)
Star | Synergy | Bonus |
---|---|---|
Doctor Strange 3 Star | Friends Level 2 | +95 Armor Rating |
Doctor Strange 4 Star | Friends Level 3 | +130 Armor Rating |
Symbiote Supreme
Add Symbiote Supreme to a team with Doctor Strange to activate the 'Mystic Masters' synergy bonus where Symbiote Supreme gets to start the fight with 1 bar of Power and DR Strange deals 50% of Base Attack as Direct Damage when Nullifying a Buff off the Opponent. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Symbiote Supreme Synergy with Doctor Strange
Star | Synergy | Bonus |
---|---|---|
Doctor Strange 3 Star | Mystic Masters | See Notes |
Doctor Strange 4 Star | Mystic Masters | See Notes |
Doctor Strange 5 Star | Mystic Masters | See Notes |
Doctor Strange 6 Star | Mystic Masters | See Notes |
Thor
When you team Doctor Strange with Thor it makes a reciprocal synergy, activating a double dose of 'Friends', increasing 'Armor Rating' for the whole team depending on the star-rating of each champion.

Doctor Strange Synergy with Thor
Star | Synergy | Bonus |
---|---|---|
Doctor Strange 3 Star | Friends Level 2 | +95 Armor Rating |
Doctor Strange 4 Star | Friends Level 3 | +130 Armor Rating |

Thor Synergy with Doctor Strange
Star | Synergy | Bonus |
---|---|---|
Doctor Strange 2 Star | Friends Level 1 | +70 Armor Rating |
Doctor Strange 3 Star | Friends Level 2 | +95 Armor Rating |
Doctor Strange 4 Star | Friends Level 3 | +130 Armor Rating |
Vision (Aarkus)
Add Vision (Aarkus) to a team with Doctor Strange to activate the 'Teammates' synergy bonus, increasing 'Perfect Block' for the whole team.

Vision (Aarkus) Synergy with Doctor Strange
Star | Synergy | Bonus |
---|---|---|
Doctor Strange 2 Star | Teammates Level 1 | +3% Perfect Block |
Doctor Strange 3 Star | Teammates Level 2 | +4% Perfect Block |
Doctor Strange 4 Star | Teammates Level 3 | +5% Perfect Block |
Doctor Strange 5 Star | Teammates Level 3 | +5% Perfect Block |
Doctor Strange 6 Star | Teammates Level 3 | +5% Perfect Block |
Void
Add Void to a team with Doctor Strange to activate the 'Enemies' synergy bonus, increasing 'Critical Rating' for the whole team.

Void Synergy with Doctor Strange
Star | Synergy | Bonus |
---|---|---|
Doctor Strange 3 Star | Enemies Level 2 | +115 Critical Rating |
Doctor Strange 4 Star | Enemies Level 3 | +155 Critical Rating |
Doctor Strange 5 Star | Enemies Level 3 | +155 Critical Rating |
Doctor Strange 6 Star | Enemies Level 3 | +155 Critical Rating |
Wolverine X-23
Adding Doctor Strange with Wolverine X-23 activates the 'Friends' synergy bonus, increasing 'Armor Rating' for the whole team.

Doctor Strange Synergy with Wolverine X-23
Star | Synergy | Bonus |
---|---|---|
Doctor Strange 3 Star | Friends Level 2 | +95 Armor Rating |
Doctor Strange 4 Star | Friends Level 3 | +130 Armor Rating |