Mister Sinister Synergy Guide

Adding Mister Sinister with Cable activates the 'Genetic Masterpiece' synergy bonus where All Mutants randomly start the fight with either +25% passive Attack Rating, +25% passive Power Rate, or +25% passive Armor Rating. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Add Colossus to a team with Mister Sinister to activate the 'Enemies' synergy bonus, increasing 'Critical Rating' for the whole team.

Adding Mister Sinister with Cyclops (Blue Team) activates the 'Blood Lines' synergy bonus where Special Attacks for Cyclops (Blue Team) and Mister Sinister have 20% Critical Rating and gain True Strike, ignoring all Armor, Resistances, Evasion and Auto Block. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Adding Mister Sinister with Cyclops (New Xavier School) activates the 'Blood Lines' synergy bonus where Special Attacks for Cyclops (New Xavier School) and Mister Sinister have 20% Critical Rating and gain True Strike, ignoring all Armor, Resistances, Evasion and Auto Block. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Add Havok to a team with Mister Sinister to activate the 'Runs in the Family' synergy bonus where Havok gains 2 Plasma Charges after each Special Attack and Well Timed Blocks against contact attacks for Mister Sinister inflict Degeneration, dealing 30% of Attack as Direct Damage overs 1 second. Cooldown 10 seconds. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Adding Mister Sinister with Kingpin activates the 'Masterminds' synergy bonus where each time the opponent uses a Special Attack against Kingpin or Mister Sinister they become Power Locked for 6 seconds. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Adding Mister Sinister with M.O.D.O.K. activates the 'Masterminds' synergy bonus where each time the opponent uses a Special Attack against M.O.D.O.K. or Mister Sinister they become Power Locked for 6 seconds. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Adding Mister Sinister with Magneto activates the 'Mutant Domination' synergy bonus where All Mutants gain +20% Passive Fury when fighting with Class Disadvantage. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Adding Mister Sinister with Magneto (Marvel Now) activates the 'Mutant Domination' synergy bonus where All Mutants gain +20% Passive Fury when fighting with Class Disadvantage. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Adding Mister Sinister with Phoenix activates the 'Blood Lines' synergy bonus where Special Attacks for Phoenix and Mister Sinister have 20% Critical Rating and gain True Strike, ignoring all Armor, Resistances, Evasion and Auto Block. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Adding Mister Sinister with Ultron activates the 'Masterminds' synergy bonus where each time the opponent uses a Special Attack against Ultron or Mister Sinister they become Power Locked for 6 seconds. Please note this is a Unique Synergy which does not stack with duplicate synergies.