Medusa Synergy Guide

Team Medusa with Black Bolt to create a perfect synergy, with each champion activating their own bonus depending on their star-rating. Medusa activates the 'Inhuman Royal Family' synergy bonus where Medusa has her Living Strands generate up to 6 Fury Buffs and Black Bolt has his Provocation buffs become permanent instead of temporary, whilst Black Bolt adds the 'Family' bonus, increasing 'Health' for the whole team. In addition, if you team Medusa, Black Bolt and Karnak together you get Inhuman Royal Family which increases Attack by +25% at the start of the fight. Please note Inhuman Royal Family is a Unique Synergy which does not stack with duplicate synergies.

Team Medusa with Karnak to create a perfect synergy, with each champion activating their own bonus depending on their star-rating. Medusa activates the 'Inhuman Royal Family' synergy bonus where Medusa can inflict up to 4 permanent Armor Breaks with her Heavy Attacks and Karnak becomes Focused 35% faster and his True Strikes last 35% longer, whilst Karnak adds the 'Family' bonus, increasing 'Health' for the whole team. Please note Inhuman Royal Family is a Unique Synergy which does not stack with duplicate synergies.