
Professor X Synergy Guide
Professor X is a Mutant class champion in the Contest of Champions who forms a synergy with 16 other characters, available as a 2-Star, 3-Star, 4-Star, 5-Star and 6-Star champion.
Professor X believed in peaceful coexistence of mutants and humans, but this all changed when Moira MacTaggert revealed to him the inevitable demise of mutantkind, unless Professor X could change his ways. Under the new moniker "X", he gave up his old dreams. No more would mutants endure the afflictions and prejudice of humankind. Under the formidable rule of X, the mutant nation of Krakoa was founded. And those who defy the nation must enter the Mindscape and face Professor X in a duel of mental strength.
Synergy Bonuses
- 'Birthright' with Professor X
- 'Drug I' with Wolverine, Wolverine X-23 or Colossus
- 'Habitat' with Storm, Storm (Pyramid X) or Emma Frost
- 'Drug L' with Cyclops (Blue Team), Cyclops (New Xavier School) or Phoenix
- 'Gateway' with Archangel, Beast or Nightcrawler
- 'Drug M' with Magneto, Magneto (Marvel Now) or Iceman

Archangel
Adding Professor X with Archangel activates the 'Gateway' synergy bonus where all Mutants and X-Men except Professor X gain 6% of a bar of Power every 10 seconds for each Cerebro Charge up to a maximum of 24%. In addition Archangel gets +30% Bleed Potency. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Professor X Synergy with Archangel
Star | Synergy | Bonus |
---|---|---|
Professor X 4 Star | Gateway | See Notes |
Professor X 5 Star | Gateway | See Notes |
Professor X 6 Star | Gateway | See Notes |
Beast
Adding Professor X with Beast activates the 'Gateway' synergy bonus where all Mutants and X-Men except Professor X gain 6% of a bar of Power every 10 seconds for each Cerebro Charge up to a maximum of 24%. In addition Beast increases the duration of Freestyle and Acrobatic Combo Success by 5 seconds. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Professor X Synergy with Beast
Star | Synergy | Bonus |
---|---|---|
Professor X 4 Star | Gateway | See Notes |
Professor X 5 Star | Gateway | See Notes |
Professor X 6 Star | Gateway | See Notes |
Colossus
Adding Professor X with Colossus activates the 'Drug I' synergy bonus where all Mutants and X-Men except Professor X gain +18% Poison Resistance for each Cerebro Charge up to a maximum of 72%. In addition Colossus gets to start each fight with 1 indefinite Armor Up Buff, granting +15% Armor Rating. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Professor X Synergy with Colossus
Star | Synergy | Bonus |
---|---|---|
Professor X 3 Star | Drug I | See Notes |
Professor X 4 Star | Drug I | See Notes |
Professor X 5 Star | Drug I | See Notes |
Professor X 6 Star | Drug I | See Notes |
Cyclops (Blue Team)
Adding Professor X with Cyclops (Blue Team) activates the 'Drug L' synergy bonus where for all Mutants and X-Men except Professor X once per fight when they would be knocked out they will instead regenerate 7.5% of their Max Health for each Cerebro Charge up to a maximum of 30% Health. In addition Beam Hits for Cyclops gain +100% Critical Damage Rating and inflict an Armor Break, reducing Armor Rating by 20% for 5 seconds. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Professor X Synergy with Cyclops (Blue Team)
Star | Synergy | Bonus |
---|---|---|
Professor X 4 Star | Drug L | See Notes |
Professor X 5 Star | Drug L | See Notes |
Professor X 6 Star | Drug L | See Notes |
Cyclops (New Xavier School)
Adding Professor X with Cyclops (New Xavier School) activates the 'Drug L' synergy bonus where for all Mutants and X-Men except Professor X once per fight when they would be knocked out they will instead regenerate 7.5% of their Max Health for each Cerebro Charge up to a maximum of 30% Health. In addition Beam Hits for Cyclops gain +100% Critical Damage Rating and inflict an Armor Break, reducing Armor Rating by 20% for 5 seconds. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Professor X Synergy with Cyclops (New Xavier School)
Star | Synergy | Bonus |
---|---|---|
Professor X 4 Star | Drug L | See Notes |
Professor X 5 Star | Drug L | See Notes |
Professor X 6 Star | Drug L | See Notes |
Emma Frost
Adding Professor X with Emma Frost activates the 'Habitat' synergy bonus where all Mutants and X-Men except Professor X gain +15% Prowess Effect Duration for each Cerebro Charge up to a maximum of 60%. In addition Emma Frost gains up to 30% increased Critical Rating scaling with her Power Meter. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Professor X Synergy with Emma Frost
Star | Synergy | Bonus |
---|---|---|
Professor X 3 Star | Habitat | See Notes |
Professor X 4 Star | Habitat | See Notes |
Professor X 5 Star | Habitat | See Notes |
Professor X 6 Star | Habitat | See Notes |
Iceman
Adding Professor X with Iceman activates the 'Drug M' synergy bonus where all Mutants and X-Men except Professor X gain a Mental Barrier with 2.5% of Current Health for each Cerebro Charge up to a maximum of Health. Whenever the Champion would take damage except from Special 3 Attacks, the Barrier takes 75% of the damage until it reaches 0 Health. In addition for Iceman when his Ice Armor shatters all Frostbite Effects expire instantly. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Professor X Synergy with Iceman
Star | Synergy | Bonus |
---|---|---|
Professor X 5 Star | Drug M | See Notes |
Professor X 6 Star | Drug M | See Notes |
Magneto
Adding Professor X with Magneto activates the 'Drug M' synergy bonus where all Mutants and X-Men except Professor X gain a Mental Barrier with 2.5% of Current Health for each Cerebro Charge up to a maximum of Health. Whenever the Champion would take damage except from Special 3 Attacks, the Barrier takes 75% of the damage until it reaches 0 Health. In addition Magneto gains +15% Attack Rating while fighting #Metal Champions. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Professor X Synergy with Magneto
Star | Synergy | Bonus |
---|---|---|
Professor X 5 Star | Drug M | See Notes |
Professor X 6 Star | Drug M | See Notes |
Magneto (Marvel Now)
Adding Professor X with Magneto (Marvel Now) activates the 'Drug M' synergy bonus where all Mutants and X-Men except Professor X gain a Mental Barrier with 2.5% of Current Health for each Cerebro Charge up to a maximum of Health. Whenever the Champion would take damage except from Special 3 Attacks, the Barrier takes 75% of the damage until it reaches 0 Health. In addition the Guidance’s bonus Attack Rating for Magneto (Marvel Now) is increased by a flat +5% or +15% on the final node of a quest. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Professor X Synergy with Magneto (Marvel Now)
Star | Synergy | Bonus |
---|---|---|
Professor X 5 Star | Drug M | See Notes |
Professor X 6 Star | Drug M | See Notes |
Nightcrawler
Adding Professor X with Nightcrawler activates the 'Gateway' synergy bonus where all Mutants and X-Men except Professor X gain 6% of a bar of Power every 10 seconds for each Cerebro Charge up to a maximum of 24%. In addition Nightcrawler gets +30% Bleed Potency. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Professor X Synergy with Nightcrawler
Star | Synergy | Bonus |
---|---|---|
Professor X 4 Star | Gateway | See Notes |
Professor X 5 Star | Gateway | See Notes |
Professor X 6 Star | Gateway | See Notes |
Phoenix
Adding Professor X with Phoenix activates the 'Drug L' synergy bonus where for all Mutants and X-Men except Professor X once per fight when they would be knocked out they will instead regenerate 7.5% of their Max Health for each Cerebro Charge up to a maximum of 30% Health. In addition when Phoenix is Overloaded she gains and indefinite Fury Passive, increasing her Attack Rating by 60% (Max 5 stacks). Please note this is a Unique Synergy which does not stack with duplicate synergies.

Professor X Synergy with Phoenix
Star | Synergy | Bonus |
---|---|---|
Professor X 4 Star | Drug L | See Notes |
Professor X 5 Star | Drug L | See Notes |
Professor X 6 Star | Drug L | See Notes |
Professor X
A totally unique synergy for Professor X, no partner required, simply add Professor X to your team to activate the Birthright bonus where all Mutants and X-Men except Professor X get +25% Special Attack Damage for each Cerebro Charge up to Max 100%. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Professor X Synergy with Professor X
Star | Synergy | Bonus |
---|---|---|
Professor X 2 Star | Birthright | See Notes |
Professor X 3 Star | Birthright | See Notes |
Professor X 4 Star | Birthright | See Notes |
Professor X 5 Star | Birthright | See Notes |
Professor X 6 Star | Birthright | See Notes |
Storm
Adding Professor X with Storm activates the 'Habitat' synergy bonus where all Mutants and X-Men except Professor X gain +15% Prowess Effect Duration for each Cerebro Charge up to a maximum of 60%. In addition Storm gets +20% Shock Potency. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Professor X Synergy with Storm
Star | Synergy | Bonus |
---|---|---|
Professor X 3 Star | Habitat | See Notes |
Professor X 4 Star | Habitat | See Notes |
Professor X 5 Star | Habitat | See Notes |
Professor X 6 Star | Habitat | See Notes |
Storm (Pyramid X)
Adding Professor X with Storm (Pyramid X) activates the 'Habitat' synergy bonus where all Mutants and X-Men except Professor X gain +15% Prowess Effect Duration for each Cerebro Charge up to a maximum of 60%. In addition Storm (Pyramid X) gets +20% Shock Potency. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Professor X Synergy with Storm (Pyramid X)
Star | Synergy | Bonus |
---|---|---|
Professor X 3 Star | Habitat | See Notes |
Professor X 4 Star | Habitat | See Notes |
Professor X 5 Star | Habitat | See Notes |
Professor X 6 Star | Habitat | See Notes |
Wolverine
Adding Professor X with Wolverine activates the 'Drug I' synergy bonus where all Mutants and X-Men except Professor X gain +18% Poison Resistance for each Cerebro Charge up to a maximum of 72%. In addition Wolverine gets +15% Crit Rating. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Professor X Synergy with Wolverine
Star | Synergy | Bonus |
---|---|---|
Professor X 3 Star | Drug I | See Notes |
Professor X 4 Star | Drug I | See Notes |
Professor X 5 Star | Drug I | See Notes |
Professor X 6 Star | Drug I | See Notes |
Wolverine X-23
Adding Professor X with Wolverine X-23 activates the 'Drug I' synergy bonus where all Mutants and X-Men except Professor X gain +18% Poison Resistance for each Cerebro Charge up to a maximum of 72%. In addition Wolverine (X-23) gets +15% Crit Rating. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Professor X Synergy with Wolverine X-23
Star | Synergy | Bonus |
---|---|---|
Professor X 3 Star | Drug I | See Notes |
Professor X 4 Star | Drug I | See Notes |
Professor X 5 Star | Drug I | See Notes |
Professor X 6 Star | Drug I | See Notes |