Mephisto Cover

Mephisto Synergy Guide

Mephisto is a Mystic class champion in the Contest of Champions who forms a synergy with 6 other characters, available as a 3-Star, 4-Star and 5-Star champion.

Mephisto is an extra-dimensional demon whose main goal is to break the will and enslave the souls of noble Champions; though he cannot take their souls himself, his treachery and deception often enough to convince his victims to give them up willingly. Mephisto is continually seeking to add more spirits to his realm, using them to his advantage whenever he sees fit. As a demon who has collected numerous souls, Mephisto is practically immortal and his fiery power is eternal.

Synergy Bonuses

Synergy Partners

  • BladeBlade
  • Doctor StrangeDoctor Strange
  • DormammuDormammu
  • Ghost RiderGhost Rider
  • HelaHela
  • MorningstarMorningstar
Mephisto


Blade

Add to a team with Mephisto to activate the 'Demon Hunter' synergy bonus where Mephisto reduces their opponent's Energy Resistance by 30% and Blade expands his Danger Sense bonuses to include all Mystic Champions. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Blade

Blade Synergy with Mephisto

Star Synergy Bonus
Blade 2 Star Demon Hunter See Notes
Blade 3 Star Demon Hunter See Notes
Blade 4 Star Demon Hunter See Notes
Blade 5 Star Demon Hunter See Notes

Doctor Strange

Adding Mephisto with activates the 'Pact with a Demon' synergy bonus where Mephisto gets +70% Incinerate Energy Damage and Doctor Strange heals an additional 70% with Life Steal. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Mephisto

Mephisto Synergy with Doctor Strange

Star Synergy Bonus
Mephisto 3 Star Pact with a Demon See Notes
Mephisto 4 Star Pact with a Demon See Notes
Mephisto 5 Star Pact with a Demon See Notes
Please note: Mephisto can also activate 'Pact with a Demon' with Ghost Rider as an alternative.

Dormammu

Adding Mephisto with activates the 'Demons' synergy bonus where both Mephisto and Dormammu gain +80% Energy Resistance while they are taking Damage over time. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Mephisto

Mephisto Synergy with Dormammu

Star Synergy Bonus
Mephisto 3 Star Demons See Notes
Mephisto 4 Star Demons See Notes
Mephisto 5 Star Demons See Notes

Ghost Rider

Adding Mephisto with activates the 'Pact with a Demon' synergy bonus where Mephisto gets +70% Incinerate Energy Damage whilst Ghost Rider gets +10% Attack at the start of the fight. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Mephisto

Mephisto Synergy with Ghost Rider

Star Synergy Bonus
Mephisto 3 Star Pact with a Demon See Notes
Mephisto 4 Star Pact with a Demon See Notes
Mephisto 5 Star Pact with a Demon See Notes
Please note: Mephisto can also activate 'Pact with a Demon' with Doctor Strange as an alternative.

Hela

Add to a team with Mephisto to activate the 'Hell Lords' synergy bonus where Mephisto regains the first Soul spent to trigger his Soul Imprisonment each fight and Hela gets to begin the fight with 1 bar of Power. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Hela

Hela Synergy with Mephisto

Star Synergy Bonus
Hela 3 Star Hell Lords See Notes
Hela 4 Star Hell Lords See Notes
Hela 5 Star Hell Lords See Notes
Hela 6 Star Hell Lords See Notes

Morningstar

Adding Mephisto with activates the 'Soul Seeker' synergy bonus where Morningstar gets to start the fight with 1 bar of Power and Mephisto gains +1 Soul at the beginning of the fight. Please note this is a Unique Synergy which does not stack with duplicate synergies.

Mephisto

Mephisto Synergy with Morningstar

Star Synergy Bonus
Mephisto 4 Star Soul Seeker See Notes
Mephisto 5 Star Soul Seeker See Notes